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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69401
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Acsl4
Name: acyl-CoA synthetase long-chain family member 4
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Acsl4increases expressionEXP 6480464CTDpirinixic acid results in increased expression of ACSL4 mRNAPMID:19162173 PMID:33983380
Acsl4increases expressionISOAcsl4 (Mus musculus)6480464CTDpirinixic acid results in increased expression of ACSL4 mRNAPMID:17118139 PMID:17950772 PMID:18301758 PMID:18467677 PMID:20813756
Acsl4multiple interactionsISOAcsl4 (Mus musculus)6480464CTD[pirinixic acid co-treated with PPARA] results in increased expression of ACSL4 mRNA; PPARA protein promotes the reaction [pirinixic acid results in increased expression of ACSL4 mRNA]PMID:17950772 PMID:18467677 PMID:20813756
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