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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69300
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slco1b2
Name: solute carrier organic anion transporter family member 1B2
Acc ID: CHEBI:74023
Term: dioscin
Definition: A spirostanyl glycoside that consists of the trisaccharide alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc attached to position 3 of diosgenin via a glycosidic linkage.
Chemical ID: MESH:C019357
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slco1b2increases expressionEXP 6480464CTDdioscin results in increased expression of SLCO1B2 mRNAPMID:27317372
Slco1b2multiple interactionsEXP 6480464CTDdioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLCO1B2 mRNA]; dioscin inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of SLCO1B2 protein]PMID:27317372
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