GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdh1 | decreases expression | EXP | | 6480464 | CTD | Cadmium Chloride results in decreased expression of CDH1 protein | PMID:15618353 | Cdh1 | decreases response to substance | EXP | | 6480464 | CTD | CDH1 results in decreased susceptibility to Cadmium Chloride | PMID:20459685 | Cdh1 | multiple interactions | EXP | | 6480464 | CTD | Cadmium Chloride inhibits the reaction [CTNNB1 protein binds to CDH1 protein binds to CTNNA1 protein]; Cadmium Chloride results in decreased expression of and affects the localization of CDH1 protein; CDH1 inhibits the reaction [Cadmium Chloride affects the localization of CTNNB1 protein]; N(6),N(6)-dimethyladenine promotes the reaction [Cadmium Chloride results in decreased expression of CDH1 protein] | PMID:15618353 PMID:19615436 PMID:20459685 | Cdh1 | decreases expression | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in decreased expression of CDH1 mRNA; Cadmium Chloride results in decreased expression of CDH1 protein | PMID:25118938 PMID:30998937 PMID:34905088 | Cdh1 | increases cleavage | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in increased cleavage of CDH1 protein | PMID:18791180 | Cdh1 | increases expression | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in increased expression of CDH1 mRNA | PMID:25882684 | Cdh1 | increases secretion | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | Cadmium Chloride results in increased secretion of CDH1 protein | PMID:18791180 | Cdh1 | multiple interactions | ISO | CDH1 (Homo sapiens) | 6480464 | CTD | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in decreased expression of CDH1 protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDH1 protein; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; Calcimycin promotes the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; Hydrogen Peroxide promotes the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [Cadmium Chloride results in increased secretion of CDH1 protein]; NOTCH1 mutant form inhibits the reaction [Cadmium Chloride results in decreased expression of CDH1 protein]; PSEN1 promotes the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; SNAI1 mutant form inhibits the reaction [Cadmium Chloride results in decreased expression of CDH1 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein] | PMID:18791180 PMID:25118938 PMID:34687772 | | ||||||||||||||||||||||
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