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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69279
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cdh1
Name: cadherin 1
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cdh1decreases expressionISOCDH1 (Homo sapiens)6480464CTDLipopolysaccharides results in decreased expression of CDH1 mRNA; Lipopolysaccharides results in decreased expression of CDH1 proteinPMID:25069516
Cdh1increases expressionISOCDH1 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of CDH1 mRNAPMID:35953652
Cdh1multiple interactionsISOCDH1 (Homo sapiens)6480464CTDResveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of CDH1 mRNA]; Resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of CDH1 protein]; Sevoflurane inhibits the reaction [Lipopolysaccharides results in increased expression of CDH1 mRNA]PMID:25069516 PMID:35953652
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