GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cdkn1b | affects expression | ISO | CDKN1B (Homo sapiens) | 6480464 | CTD | sodium arsenite affects the expression of CDKN1B mRNA | PMID:24535192 | Cdkn1b | decreases expression | ISO | CDKN1B (Homo sapiens) | 6480464 | CTD | sodium arsenite results in decreased expression of CDKN1B protein | PMID:32890875 | Cdkn1b | decreases expression | ISO | Cdkn1b (Mus musculus) | 6480464 | CTD | sodium arsenite results in decreased expression of CDKN1B protein | PMID:10764629 | Cdkn1b | increases expression | ISO | CDKN1B (Homo sapiens) | 6480464 | CTD | sodium arsenite results in increased expression of CDKN1B protein | PMID:29039521 PMID:30123091 | Cdkn1b | multiple interactions | ISO | CDKN1B (Homo sapiens) | 6480464 | CTD | [sodium arsenite co-treated with tetrandrine] results in increased expression of CDKN1B protein; [sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein; Lapatinib inhibits the reaction [sodium arsenite results in decreased expression of CDKN1B protein]; SB 203580 inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased expression of CDKN1B protein]; sodium arsenite promotes the reaction [CDK4 protein binds to CDKN1B protein] | PMID:19082730 PMID:29039521 PMID:30123091 PMID:32890875 | Cdkn1b | multiple interactions | ISO | Cdkn1b (Mus musculus) | 6480464 | CTD | 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole affects the reaction [[CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the expression of PTGS2 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole affects the reaction [[CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the phosphorylation of CREB1 protein]; [CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the expression of PTGS2 mRNA; [CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the expression of PTGS2 protein; [CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the phosphorylation of CREB1 protein; [CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the phosphorylation of MAPK1 protein; [CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the phosphorylation of MAPK3 protein; [sodium arsenite results in increased abundance of arsenite] affects the reaction [CDKN1B protein affects the expression of PTGS2 mRNA]; CDKN1B protein affects the reaction [[sodium arsenite results in increased abundance of arsenite] which results in increased expression of PTGS2 protein]; CDKN1B protein affects the reaction [sodium arsenite results in increased activity of CASP3 protein]; CDKN1B protein affects the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; CDKN1B protein affects the reaction [sodium arsenite results in increased phosphorylation of JUN protein]; CDKN1B protein affects the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]; CDKN1B protein affects the reaction [sodium arsenite results in increased phosphorylation of MAPK9 protein]; CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]; CDKN1B protein inhibits the reaction [sodium arsenite results in increased activity of AKT1 protein]; CDKN1B protein inhibits the reaction [sodium arsenite results in increased activity of MAP2K4 protein]; CDKN1B protein inhibits the reaction [sodium arsenite results in increased expression of HSPA1A mRNA]; CDKN1B protein inhibits the reaction [sodium arsenite results in increased expression of HSPA1A protein]; CDKN1B protein inhibits the reaction [sodium arsenite results in increased expression of HSPB1 mRNA]; CDKN1B protein inhibits the reaction [sodium arsenite results in increased expression of HSPB1 protein]; CREB1 protein affects the reaction [[CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the expression of PTGS2 mRNA]; CREB1 protein affects the reaction [[CDKN1B protein affects the susceptibility to [sodium arsenite results in increased abundance of arsenite]] which affects the expression of PTGS2 protein] | PMID:20566634 PMID:23639288 | |
Go Back to source page | Continue to Ontology report |