GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr1i2 | multiple interactions | EXP | | 6480464 | CTD | Atorvastatin promotes the reaction [Dietary Fats results in increased expression of NR1I2 protein] | PMID:26616219 | Nr1i2 | increases expression | ISO | NR1I2 (Homo sapiens) | 6480464 | CTD | Atorvastatin results in increased expression of NR1I2 protein | PMID:26616219 | Nr1i2 | multiple interactions | ISO | NR1I2 (Homo sapiens) | 6480464 | CTD | [Atorvastatin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Atorvastatin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of GCK protein]; NR1I2 protein promotes the reaction [Atorvastatin results in decreased expression of SLC2A2 protein] | PMID:24204015 PMID:26616219 | Nr1i2 | multiple interactions | ISO | Nr1i2 (Mus musculus) | 6480464 | CTD | Atorvastatin binds to and results in increased activity of NR1I2 protein | PMID:15986414 | | ||||||||||||||||||||||
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