GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of TGFB1 mRNA; bisphenol A results in decreased expression of TGFB1 protein | PMID:20219716 PMID:25181051 PMID:34097993 PMID:34947998 | Tgfb1 | increases expression | EXP | | 6480464 | CTD | bisphenol A results in increased expression of TGFB1 mRNA; bisphenol A results in increased expression of TGFB1 protein | PMID:27025157 PMID:29323181 PMID:35465754 PMID:38027817 | Tgfb1 | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of TGFB1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]; [bisphenol A co-treated with Dietary Fats] results in increased expression of TGFB1 mRNA; [bisphenol A co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of TGFB1 mRNA; [icatibant co-treated with Captopril] inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]; Captopril inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]; ESR2 protein affects the reaction [bisphenol A results in decreased expression of TGFB1 mRNA]; Fluvastatin inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]; Fluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of TGFB1 mRNA]; Fulvestrant inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]; Losartan inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]; taxifolin inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]; taxifolin promotes the reaction [Fluvastatin inhibits the reaction [bisphenol A results in increased expression of TGFB1 protein]]; TGFB1 protein inhibits the reaction [bisphenol A results in decreased expression of BGLAP mRNA]; TGFB1 protein inhibits the reaction [bisphenol A results in decreased expression of RUNX2 mRNA]; TGFB1 protein inhibits the reaction [bisphenol A results in decreased expression of SP7 mRNA] | PMID:25112833 PMID:25607892 PMID:27025157 PMID:34097993 PMID:35465754 PMID:38027817 | Tgfb1 | affects expression | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | bisphenol A affects the expression of TGFB1 mRNA | PMID:21826169 PMID:30903817 | Tgfb1 | decreases expression | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased expression of TGFB1 protein | PMID:31675489 | Tgfb1 | decreases expression | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased expression of TGFB1 mRNA | PMID:31108126 PMID:37105096 | Tgfb1 | decreases secretion | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased secretion of TGFB1 protein | PMID:31108126 | Tgfb1 | increases expression | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in increased expression of TGFB1 protein | PMID:33024228 PMID:35069845 | Tgfb1 | increases expression | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of TGFB1 mRNA; bisphenol A results in increased expression of TGFB1 protein | PMID:24809654 PMID:26063408 PMID:30951980 PMID:32156529 | Tgfb1 | increases secretion | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased secretion of TGFB1 protein | PMID:35051763 | Tgfb1 | multiple interactions | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; bisphenol A promotes the reaction [ESRRA protein binds to TGFB1 promoter]; ESRRA protein promotes the reaction [bisphenol A results in increased expression of TGFB1 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein] | PMID:25128825 PMID:35069845 | Tgfb1 | multiple interactions | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | 4-(2-phenyl-5,7-bis(trifluoromethyl)pyrazolo(1,5-a)pyrimidin-3-yl)phenol inhibits the reaction [bisphenol A results in increased secretion of TGFB1 protein]; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in decreased expression of TGFB1 mRNA; [bisphenol A co-treated with Tretinoin] results in decreased expression of TGFB1 mRNA; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of TGFB1 protein]; bisphenol A promotes the reaction [Dietary Fats results in increased expression of TGFB1 mRNA]; ESR2 protein affects the reaction [bisphenol A results in increased secretion of TGFB1 protein] | PMID:30951980 PMID:33265944 PMID:35051763 PMID:35739755 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |