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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:22977
Term: cadmium atom
Definition: A zinc group element atom that has formula Cd.
Chemical ID: MESH:D002104
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1multiple interactionsEXP 6480464CTD[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein]PMID:25240712
Tgfb1multiple interactionsISOTGFB1 (Homo sapiens)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TGFB1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TGFB1 mRNA; MitoTEMPO inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TGFB1 mRNA]; PPARG protein inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TGFB1 mRNA]PMID:32917723 PMID:36602393
Tgfb1multiple interactionsISOTgfb1 (Mus musculus)6480464CTD[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TGFB1 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TGFB1 mRNAPMID:31614173 PMID:32917723 PMID:33359024 PMID:36200916 PMID:37022104
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