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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69051
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tgfb1
Name: transforming growth factor, beta 1
Acc ID: CHEBI:136004
Term: linsidomine
Definition: null
Chemical ID: MESH:C002385
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfb1decreases expressionEXP 6480464CTDlinsidomine results in decreased expression of TGFB1 mRNA; linsidomine results in decreased expression of TGFB1 proteinPMID:11994256
Tgfb1increases activityEXP 6480464CTDlinsidomine results in increased activity of TGFB1 proteinPMID:11994256
Tgfb1multiple interactionsEXP 6480464CTD2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide inhibits the reaction [linsidomine results in decreased expression of TGFB1 mRNA]; 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide inhibits the reaction [linsidomine results in decreased expression of TGFB1 protein]PMID:11994256
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