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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68997 Species: Homo sapiens RGD Object: Gene Symbol: IGF1R Name: insulin-like growth factor 1 receptor

Acc ID: CHEBI:16330 Term: 17beta-hydroxy-5alpha-androstan-3-one Definition: An androgen that has formula C19H30O2. CasRN: 521-18-6 Chemical ID: MESH:D013196

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Nordihydroguaiaretic Acid inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R protein] Nordihydroguaiaretic Acid inhibits the reaction [Dihydrotestosterone results in increased expression of IGF1R mRNA]	PMID:18491370
increases expression	EXP		6480464	CTD	Dihydrotestosterone results in increased expression of IGF1R protein Dihydrotestosterone results in increased expression of IGF1R mRNA	PMID:18491370