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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68436
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gucy1a1
Name: guanylate cyclase 1 soluble subunit alpha 1
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gucy1a1increases expressionISOGUCY1A1 (Homo sapiens)6480464CTDLipopolysaccharides results in increased expression of GUCY1A1 mRNAPMID:35811015
Gucy1a1multiple interactionsISOGUCY1A1 (Homo sapiens)6480464CTDS-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of GUCY1A1 mRNA]PMID:35811015
Gucy1a1multiple interactionsISOGucy1a1 (Mus musculus)6480464CTDESR1 protein affects the reaction [Lipopolysaccharides affects the expression of GUCY1A1 mRNA]; ESR1 protein affects the reaction [Lipopolysaccharides affects the expression of GUCY1A1 protein]PMID:17158209
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