GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Epas1 | increases expression | EXP | | 6480464 | CTD | Copper results in increased expression of EPAS1 mRNA | PMID:30556269 | Epas1 | increases expression | ISO | Epas1 (Mus musculus) | 6480464 | CTD | Copper deficiency results in increased expression of EPAS1 protein | PMID:23555700 | Epas1 | multiple interactions | ISO | EPAS1 (Homo sapiens) | 6480464 | CTD | [Chelating Agents binds to Copper] which results in increased expression of EPAS1 mRNA | PMID:30911355 | Epas1 | multiple interactions | ISO | Epas1 (Mus musculus) | 6480464 | CTD | EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of CYBRD1 mRNA]; EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of SLC11A2 mRNA alternative form]; EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of SLC40A1 mRNA] | PMID:23555700 | | ||||||||||||||||||||||
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