GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kcnd2 | decreases expression | EXP | | 6480464 | CTD | Phenylephrine results in decreased expression of KCND2 mRNA; Phenylephrine results in decreased expression of KCND2 protein | PMID:16385079 PMID:17060317 | Kcnd2 | decreases response to substance | EXP | | 6480464 | CTD | KCND2 protein results in decreased susceptibility to Phenylephrine | PMID:12403671 | Kcnd2 | multiple interactions | EXP | | 6480464 | CTD | CABIN1 protein promotes the reaction [Phenylephrine results in decreased expression of KCND2 mRNA]; CABIN1 protein promotes the reaction [Phenylephrine results in decreased expression of KCND2 protein]; KCND2 protein inhibits the reaction [Phenylephrine results in increased activity of NFATC1 protein]; KCND2 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA] | PMID:12403671 PMID:17060317 | |
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