GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | affects expression | EXP | | 6480464 | CTD | nickel chloride affects the expression of CCND1 mRNA | PMID:22546817 | Ccnd1 | decreases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | nickel chloride results in decreased expression of CCND1 mRNA | PMID:17312168 | Ccnd1 | decreases phosphorylation | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | nickel chloride results in decreased phosphorylation of CCND1 protein | PMID:18792914 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [nickel chloride results in decreased phosphorylation of CCND1 protein]; nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein | PMID:18792914 | Ccnd1 | multiple interactions | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | CHUK protein affects the reaction [nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein]; nickel chloride results in decreased expression of and results in increased degradation of CCND1 protein | PMID:18792914 | |
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