GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | increases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | DDT results in increased expression of CCND1 protein | PMID:24968063 PMID:8927716 PMID:9049186 | Ccnd1 | increases expression | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | DDT results in increased expression of CCND1 mRNA; DDT results in increased expression of CCND1 protein | PMID:23684557 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of CCND1 protein] | PMID:24968063 | Ccnd1 | multiple interactions | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | DDT promotes the reaction [ESR1 protein binds to CCND1 promoter]; DDT promotes the reaction [FOS protein binds to CCND1 promoter] | PMID:23684557 | |
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