GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | decreases expression | EXP | | 6480464 | CTD | Oxygen deficiency results in decreased expression of CCND1 protein | PMID:26476374 | Ccnd1 | increases expression | EXP | | 6480464 | CTD | Oxygen deficiency results in increased expression of CCND1 mRNA; Oxygen deficiency results in increased expression of CCND1 protein | PMID:36940862 | Ccnd1 | multiple interactions | EXP | | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of CCND1 protein]; [kaempferol co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [Oxygen deficiency results in increased expression of CCND1 protein]; kaempferol inhibits the reaction [Oxygen deficiency results in increased expression of CCND1 mRNA]; kaempferol inhibits the reaction [Oxygen deficiency results in increased expression of CCND1 protein]; Quercetin inhibits the reaction [Oxygen deficiency results in decreased expression of CCND1 protein]; Sildenafil Citrate inhibits the reaction [Oxygen deficiency results in increased expression of CCND1 protein] | PMID:26476374 PMID:36940862 | Ccnd1 | decreases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in decreased expression of CCND1 mRNA | PMID:26516004 | Ccnd1 | increases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Oxygen deficiency results in increased expression of CCND1 mRNA | PMID:17914565 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | [Betulinic Acid co-treated with Oxygen deficiency] results in decreased expression of CCND1 protein; [Oxygen co-treated with Ozone] results in decreased expression of CCND1 mRNA; Cannabidiol promotes the reaction [[Oxygen co-treated with Ozone] results in decreased expression of CCND1 mRNA] | PMID:32992648 PMID:33181113 | Ccnd1 | multiple interactions | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | [Butylated Hydroxytoluene co-treated with Oxygen] results in increased expression of CCND1 protein; [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA; cyclopamine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]; cyclopamine inhibits the reaction [polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA]]; polydatin promotes the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of CCND1 mRNA] | PMID:16272459 PMID:27481074 | | ||||||||||||||||||||||
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