GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccnd1 | multiple interactions | EXP | | 6480464 | CTD | Tretinoin inhibits the reaction [sodium arsenite results in decreased expression of CCND1 mRNA]; Tretinoin inhibits the reaction [sodium arsenite results in decreased expression of CCND1 protein] | PMID:21964460 | Ccnd1 | decreases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Tretinoin results in decreased expression of CCND1 mRNA; Tretinoin results in decreased expression of CCND1 protein | PMID:17387344 PMID:17453147 PMID:20507312 PMID:21924320 PMID:30093655 | Ccnd1 | decreases expression | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | Tretinoin results in decreased expression of CCND1 mRNA; Tretinoin results in decreased expression of CCND1 protein | PMID:18425745 PMID:22498432 | Ccnd1 | decreases response to substance | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | CCND1 protein results in decreased susceptibility to Tretinoin | PMID:11595732 | Ccnd1 | increases expression | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased expression of CCND1 mRNA | PMID:15498508 PMID:33167477 | Ccnd1 | increases expression | ISO | Ccnd1 (Mus musculus) | 6480464 | CTD | Tretinoin results in increased expression of CCND1 protein | PMID:15231690 | Ccnd1 | increases ubiquitination | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | Tretinoin results in increased ubiquitination of CCND1 protein | PMID:11595732 | Ccnd1 | multiple interactions | ISO | CCND1 (Homo sapiens) | 6480464 | CTD | acetylleucyl-leucyl-norleucinal inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]; Arsenic Trioxide promotes the reaction [Tretinoin results in decreased expression of CCND1 protein]; Lithium Chloride inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]; SB 216763 inhibits the reaction [Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein]; Tretinoin inhibits the reaction [[[PDGFB protein binds to PDGFB protein] which co-treated with INS protein] results in increased expression of CCND1 protein]; Tretinoin inhibits the reaction [Benzo(a)pyrene results in increased expression of CCND1 protein]; Tretinoin inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; Tretinoin promotes the reaction [Arsenic Trioxide results in decreased expression of CCND1 protein]; Tretinoin results in increased degradation of and results in decreased expression of CCND1 protein | PMID:11348869 PMID:16024653 PMID:16406622 PMID:16565789 PMID:30093655 | | ||||||||||||||||||||||
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