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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68371
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mtor
Name: mechanistic target of rapamycin kinase
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mtormultiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MTOR protein]PMID:21195169 PMID:26804764
Mtormultiple interactionsISOMTOR (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Antimycin A results in increased expression of MTOR mRNA]; Acetylcysteine inhibits the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Biological Products results in decreased expression of MTOR protein modified form]; Acetylcysteine inhibits the reaction [butein results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased phosphorylation of MTOR protein]PMID:23000059 PMID:27106530 PMID:28025121 PMID:28219700 PMID:28600122 PMID:29604266 PMID:30797898 PMID:33002460 PMID:35130734 PMID:35430258 PMID:36810933 PMID:37148176
Mtormultiple interactionsISOMtor (Mus musculus)6480464CTDAcetylcysteine inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]PMID:31368586 PMID:31982503 PMID:36709824
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