GENE - CHEMICAL INTERACTIONS REPORT
mechanistic target of rapamycin (serine/threonine kinase)
The 17beta-isomer of estradiol.
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
increases activity ISO RGD:68533 6480464 CTD Estradiol results in increased activity of MTOR protein PMID:16024245 affects activity ISO RGD:68533 6480464 CTD Estradiol affects the activity of MTOR protein PMID:16033851 multiple interactions ISO RGD:68533 6480464 CTD everolimus inhibits the reaction [Estradiol affects the activity of MTOR protein] letrozole inhibits the reaction [Estradiol affects the activity of MTOR protein] PMID:16033851 multiple interactions EXP 6480464 CTD [Estradiol co-treated with Progesterone co-treated with Methylnitrosourea] results in increased phosphorylation of MTOR protein PMID:22465879