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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68334
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S1pr2
Name: sphingosine-1-phosphate receptor 2
Acc ID: CHEBI:27385
Term: tetrachloromethane
Definition: A chlorocarbon that is methane in which all the hydrogens have been replaced by chloro groups.
Chemical ID: MESH:D002251
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S1pr2increases expressionISOS1pr2 (Mus musculus)6480464CTDCarbon Tetrachloride results in increased expression of S1PR2 mRNAPMID:17341687
S1pr2multiple interactionsISOS1pr2 (Mus musculus)6480464CTDS1PR2 protein affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; S1PR2 protein affects the reaction [Carbon Tetrachloride results in increased expression of PDGFB mRNA]; S1PR2 protein affects the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; S1PR2 protein affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]PMID:17341687
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