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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67383
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Prkcd
Name: protein kinase C, delta
Acc ID: CHEBI:35154
Term: manganese(0)
Definition: An elemental manganese that has formula Mn.
Chemical ID: MESH:D008345
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Prkcdincreases phosphorylationEXP 6480464CTDManganese results in increased phosphorylation of PRKCD proteinPMID:21812036
Prkcdmultiple interactionsEXP 6480464CTDManganese promotes the reaction [PRKCD protein binds to SLC1A5 protein]; Manganese promotes the reaction [PRKCD protein binds to SLC38A3 protein]; Manganese results in increased cleavage of and results in increased activity of PRKCD proteinPMID:21812036 PMID:25416158
Prkcdmultiple interactionsISOPRKCD (Homo sapiens)6480464CTDSNCA protein inhibits the reaction [Manganese results in increased cleavage of and results in increased activity of PRKCD protein]PMID:25416158
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