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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631434
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bbc3
Name: Bcl-2 binding component 3
Acc ID: CHEBI:50131
Term: 5-aza-2'-deoxycytidine
Definition: A 2'-deoxyribonucleoside that has formula C8H12N4O4.
Chemical ID: MESH:C014347
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bbc3affects methylationISOBBC3 (Homo sapiens)6480464CTDDecitabine affects the methylation of BBC3 promoterPMID:17488656
Bbc3increases expressionISOBBC3 (Homo sapiens)6480464CTDDecitabine results in increased expression of BBC3 proteinPMID:19732952
Bbc3multiple interactionsISOBBC3 (Homo sapiens)6480464CTD[Decitabine affects the methylation of BBC3 gene] which affects the expression of BBC3 mRNA; [Decitabine affects the methylation of BBC3 gene] which affects the expression of BBC3 proteinPMID:18573879
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