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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631409
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90aa1
Name: heat shock protein 90 alpha family class A member 1
Acc ID: CHEBI:49900
Term: arsenous acid
Definition: An arsenic oxoacid consisting of three hydroxy groups attached to a central arsenic atom.
Chemical ID: MESH:C032793
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90aa1increases expressionEXP 6480464CTDArsenic Trioxide results in increased expression of HSP90AA1 proteinPMID:27592447
Hsp90aa1affects response to substanceISOHSP90AA1 (Homo sapiens)6480464CTDHSP90AA1 protein affects the susceptibility to Arsenic TrioxidePMID:19371599
Hsp90aa1increases expressionISOHSP90AA1 (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of HSP90AA1 mRNA; Arsenic Trioxide results in increased expression of HSP90AA1 proteinPMID:11940349 PMID:18081892 PMID:19364129 PMID:19417148 PMID:20458559 PMID:22922937 PMID:29633893
Hsp90aa1multiple interactionsISOHSP90AA1 (Homo sapiens)6480464CTDsulforaphane promotes the reaction [Arsenic Trioxide results in increased expression of HSP90AA1 protein]PMID:22922937
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