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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631365
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nampt
Name: nicotinamide phosphoribosyltransferase
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Namptdecreases expressionISONAMPT (Homo sapiens)6480464CTDGlucose results in decreased expression of NAMPT mRNAPMID:20068143
Namptincreases expressionISONAMPT (Homo sapiens)6480464CTDGlucose results in increased expression of NAMPT mRNAPMID:23536823
Namptincreases secretionISONAMPT (Homo sapiens)6480464CTDGlucose results in increased secretion of NAMPT proteinPMID:23536823
Namptmultiple interactionsISONAMPT (Homo sapiens)6480464CTDDiazoxide inhibits the reaction [Glucose results in increased secretion of NAMPT protein]; Nifedipine inhibits the reaction [Glucose results in increased secretion of NAMPT protein]PMID:23536823
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