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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631345
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcg2
Name: ATP binding cassette subfamily G member 2
Acc ID: CHEBI:80230
Term: Potassium 2,6-dihydroxytriazinecarboxylate
Definition: An organic molecular entity that has formula C4H2KN3O4.
Chemical ID: MESH:C489337
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg2increases expressionISOAbcg2 (Mus musculus)6480464CTDpotassium oxonate results in increased expression of ABCG2 proteinPMID:22865646
Abcg2multiple interactionsISOAbcg2 (Mus musculus)6480464CTD4-hydroxystilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; Allopurinol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; mulberroside A inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; polydatin inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; pterostilbene inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]; resveratrol inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein]PMID:22865646
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