GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Angpt1 | decreases expression | ISO | Angpt1 (Mus musculus) | 6480464 | CTD | Doxorubicin results in decreased expression of ANGPT1 mRNA | PMID:25896364 | Angpt1 | decreases expression | ISO | ANGPT1 (Homo sapiens) | 6480464 | CTD | Doxorubicin results in decreased expression of ANGPT1 mRNA | PMID:29803840 | Angpt1 | decreases response to substance | ISO | ANGPT1 (Homo sapiens) | 6480464 | CTD | ANGPT1 protein results in decreased susceptibility to Doxorubicin | PMID:15763944 | Angpt1 | multiple interactions | ISO | ANGPT1 (Homo sapiens) | 6480464 | CTD | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein results in decreased susceptibility to Doxorubicin]; ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of FAS mRNA]; ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of FASLG mRNA]; ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein] | PMID:15763944 | | ||||||||||||||||||||||
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