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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pla2g6
Name: phospholipase A2 group VI
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pla2g6increases expressionEXP 6480464CTDpirinixic acid results in increased expression of PLA2G6 mRNAPMID:19162173
Pla2g6increases expressionISOPla2g6 (Mus musculus)6480464CTDpirinixic acid results in increased expression of PLA2G6 mRNAPMID:17426115 PMID:18301758 PMID:19850644 PMID:20059764 PMID:20813756 PMID:23811191
Pla2g6multiple interactionsISOPla2g6 (Mus musculus)6480464CTDPPARA protein promotes the reaction [pirinixic acid results in decreased expression of PLA2G6 mRNA]; PPARA protein promotes the reaction [pirinixic acid results in increased expression of PLA2G6 mRNA]PMID:19850644 PMID:20059764
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