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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9increases expressionISOMapk9 (Mus musculus)6480464CTDchromium hexavalent ion results in increased expression of MAPK9 proteinPMID:19895865
Mapk9increases phosphorylationISOMAPK9 (Homo sapiens)6480464CTDchromium hexavalent ion results in increased phosphorylation of MAPK9 proteinPMID:17045426
Mapk9increases phosphorylationISOMapk9 (Mus musculus)6480464CTDchromium hexavalent ion results in increased phosphorylation of MAPK9 proteinPMID:19654923 PMID:19895865
Mapk9multiple interactionsISOMapk9 (Mus musculus)6480464CTD[Arsenates co-treated with chromium hexavalent ion] results in increased expression of MAPK9 protein; [Arsenates co-treated with chromium hexavalent ion] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK9 protein]; MAP2K7 protein promotes the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK9 protein]PMID:19654923 PMID:19895865
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