GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Trpv1 | increases expression | EXP | | 6480464 | CTD | Morphine results in increased expression of TRPV1; Morphine results in increased expression of TRPV1 protein | PMID:18774343 PMID:20719804 | Trpv1 | multiple interactions | EXP | | 6480464 | CTD | [N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-3-(2-(piperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)acrylamide binds to and results in decreased activity of TRPV1 protein] which results in decreased susceptibility to Morphine | PMID:18774343 | Trpv1 | affects activity | ISO | Trpv1 (Mus musculus) | 6480464 | CTD | Morphine affects the activity of TRPV1 protein | PMID:22189556 | Trpv1 | affects response to substance | ISO | Trpv1 (Mus musculus) | 6480464 | CTD | TRPV1 protein affects the susceptibility to Morphine | PMID:18774343 | Trpv1 | multiple interactions | ISO | Trpv1 (Mus musculus) | 6480464 | CTD | [N-(7-hydroxy-5,6,7,8-tetrahydronaphthalen-1-yl)-3-(2-(piperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl)acrylamide binds to and results in decreased activity of TRPV1 protein] which results in decreased susceptibility to Morphine | PMID:18774343 | |
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