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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628709
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a18
Name: cytochrome P450, family 3, subfamily a, polypeptide 18
Acc ID: CHEBI:28119
Term: 2,3,7,8-tetrachlorodibenzodioxine
Definition: A polychlorinated dibenzodioxine that has formula C12H4Cl4O2.
Chemical ID: MESH:D013749
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a18affects expressionEXP 6480464CTDTetrachlorodibenzodioxin affects the expression of CYP3A18 mRNAPMID:22298810
Cyp3a18decreases expressionEXP 6480464CTDTetrachlorodibenzodioxin results in decreased expression of CYP3A18 mRNAPMID:21215274 PMID:21724226
Cyp3a18affects expressionISOCYP3A43 (Homo sapiens)6480464CTDTetrachlorodibenzodioxin affects the expression of CYP3A43 mRNAPMID:22298810
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