GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il12b | increases expression | ISO | IL12B (Homo sapiens) | 6480464 | CTD | resiquimod results in increased expression of IL12B protein | PMID:18490488 | Il12b | increases expression | ISO | Il12b (Mus musculus) | 6480464 | CTD | resiquimod results in increased expression of IL12B protein | PMID:15187114 | Il12b | multiple interactions | ISO | IL12B (Homo sapiens) | 6480464 | CTD | [Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]; [Acetylmuramyl-Alanyl-Isoglutamine co-treated with resiquimod co-treated with IFNG protein] results in increased expression of IL12B mRNA; [beta-Glucans co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]; [Lipopolysaccharides co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL12B protein]; [Lipopolysaccharides co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]; [Zymosan co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]; [Zymosan co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]; [Zymosan co-treated with resiquimod] results in increased expression of IL12B protein; IFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of [IL12A protein binds to IL12B protein]]; IFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of [IL12B protein binds to IL23A protein]]; IFNG protein promotes the reaction [[Zymosan co-treated with resiquimod] results in increased expression of IL12B protein]; resiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of [IL12A protein binds to IL12B protein]]; resiquimod promotes the reaction [[Acetylmuramyl-Alanyl-Isoglutamine co-treated with Pam(3)CSK(4) peptide co-treated with IFNG protein] results in increased expression of IL12B protein]; resiquimod promotes the reaction [beta-Glucans results in increased expression of [IL12B protein binds to IL23A protein]]; resiquimod promotes the reaction [beta-Glucans results in increased expression of IL12B protein] | PMID:18490488 | Il12b | multiple interactions | ISO | Il12b (Mus musculus) | 6480464 | CTD | [resiquimod co-treated with Lipopolysaccharides] results in increased secretion of [IL12A protein binds to IL12B protein]; resiquimod inhibits the reaction [[IFNG protein co-treated with Lipopolysaccharides] results in increased secretion of IL12B protein]; Simvastatin promotes the reaction [resiquimod results in increased expression of IL12B protein] | PMID:15187114 PMID:15851485 PMID:23890009 | | ||||||||||||||||||||||
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