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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62288 Species: Mus musculus RGD Object: Gene Symbol: F2 Name: coagulation factor II

Acc ID: CHEBI:15422 Term: ATP Definition: A purine ribonucleoside 5'-triphosphate that has formula C10H16N5O13P3. CasRN: 56-65-5 Chemical ID: MESH:D000255

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1353256	6480464	CTD	Fendiline affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate] calmidazolium affects the reaction [F2 protein results in increased secretion of Adenosine Triphosphate]	PMID:2030746
increases secretion	ISO	RGD:1353256	6480464	CTD	F2 protein results in increased secretion of Adenosine Triphosphate	PMID:2030746
increases abundance	ISO	RGD:1353256	6480464	CTD	F2 protein results in increased abundance of Adenosine Triphosphate	PMID:15342215
multiple interactions	ISO	RGD:1353256	6480464	CTD	Quercetin inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate] resveratrol inhibits the reaction [F2 protein results in increased abundance of Adenosine Triphosphate]	PMID:15342215