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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621805
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b3
Name: hydroxysteroid (17-beta) dehydrogenase 3
Acc ID: CHEBI:4042
Term: cypermethrin
Definition: A carboxylic ester resulting from the formal condensation between 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and the alcoholic hydroxy group of hydroxy(3-phenoxyphenyl)acetonitrile.
Chemical ID: MESH:C017160
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b3multiple interactionsEXP 6480464CTD[Allethrins co-treated with cyhalothrin co-treated with cypermethrin co-treated with decamethrin co-treated with fenvalerate] results in decreased expression of HSD17B3 mRNA; [cypermethrin co-treated with decamethrin co-treated with fenvalerate co-treated with cyhalothrin co-treated with Allethrins] affects the expression of HSD17B3 mRNAPMID:33051911 PMID:33396045 PMID:34896426
Hsd17b3decreases expressionISOHsd17b3 (Mus musculus)6480464CTDcypermethrin results in decreased expression of HSD17B3 mRNA; cypermethrin results in decreased expression of HSD17B3 proteinPMID:24810582
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