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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621654
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tsc22d3
Name: TSC22 domain family, member 3
Acc ID: CHEBI:25812
Term: ozone
Definition: An elemental molecule with formula O3. An explosive, pale blue gas (b.p. -112degreeC) that has a characteristic, pungent odour, it is continuously produced in the upper atmosphere by the action of solar ultraviolet radiation on atmospheric oxygen. It is an antimicrobial agent used in the production of bottled water, as well as in the treatment of meat, poultry and other foodstuffs.
Chemical ID: MESH:D010126
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tsc22d3decreases expressionEXP 6480464CTDOzone results in decreased expression of TSC22D3 mRNAPMID:28549673
Tsc22d3increases expressionEXP 6480464CTDOzone results in increased expression of TSC22D3 mRNAPMID:23805001 PMID:27037194 PMID:28623178 PMID:34051339
Tsc22d3multiple interactionsEXP 6480464CTD[Air Pollutants results in increased abundance of Ozone] which results in increased expression of TSC22D3 mRNA; Metyrapone inhibits the reaction [[Air Pollutants results in increased abundance of Ozone] which results in increased expression of TSC22D3 mRNA]; Metyrapone inhibits the reaction [Ozone results in increased expression of TSC22D3 mRNA]PMID:27037194 PMID:31520820
Tsc22d3multiple interactionsISOTsc22d3 (Mus musculus)6480464CTD[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of TSC22D3 mRNA; [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of TSC22D3 mRNAPMID:27106289 PMID:34911549
Tsc22d3multiple interactionsISOTSC22D3 (Homo sapiens)6480464CTD[Air Pollutants results in increased abundance of Ozone] which affects the expression of TSC22D3 mRNAPMID:35430440
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