Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621619
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Keap1
Name: Kelch-like ECH-associated protein 1
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Keap1affects bindingISOKeap1 (Mus musculus)6480464CTDZinc binds to KEAP1 proteinPMID:15865434
Keap1multiple interactionsISOKeap1 (Mus musculus)6480464CTD4,4'-dipyridyl disulfide promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]]; 4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]; Hydrogen Peroxide promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]]; sulforaphane promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]]; Zinc inhibits the reaction [Cobalt binds to KEAP1 protein]PMID:15865434
Go Back to source page   Continue to Ontology report