GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mapk8 | affects expression | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | trichostatin A affects the expression of MAPK8 mRNA | PMID:28542535 | Mapk8 | decreases expression | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | trichostatin A results in decreased expression of MAPK8 mRNA | PMID:22723015 PMID:26272509 | Mapk8 | multiple interactions | ISO | MAPK8 (Homo sapiens) | 6480464 | CTD | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MAPK8 mRNA; [perifosine co-treated with trichostatin A] results in increased activity of MAPK8 protein; DUSP1 mutant form inhibits the reaction [trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]]; trichostatin A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] | PMID:15781658 PMID:21911040 PMID:27188386 | | ||||||||||||||||||||||
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