GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kcnh2 | affects binding | ISO | KCNH2 (Homo sapiens) | 6480464 | CTD | Cisapride binds to KCNH2 protein | PMID:18701618 PMID:19260734 | Kcnh2 | affects localization | ISO | KCNH2 (Homo sapiens) | 6480464 | CTD | Cisapride affects the localization of KCNH2 protein mutant form | PMID:10531299 PMID:11741928 | Kcnh2 | decreases activity | ISO | KCNH2 (Homo sapiens) | 6480464 | CTD | Cisapride results in decreased activity of KCNH2 protein | PMID:11741928 PMID:15306208 PMID:15671647 PMID:15740727 PMID:17513944 PMID:24052561 PMID:24830940 PMID:27553911 PMID:28551711 PMID:30561737 PMID:9395068 | Kcnh2 | multiple interactions | ISO | KCNH2 (Homo sapiens) | 6480464 | CTD | beta-Cyclodextrins analog inhibits the reaction [Cisapride results in decreased activity of KCNH2 protein]; Cisapride binds to and results in decreased activity of KCNH2 protein; Cisapride inhibits the reaction [KCNH2 protein results in increased transport of Thallium] | PMID:11005845 PMID:12388285 PMID:15272206 PMID:17513944 PMID:19583963 PMID:21158687 | |
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