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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621414
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnh2
Name: potassium voltage-gated channel subfamily H member 2
Acc ID: CHEBI:17634
Term: D-glucose
Definition: A glucose with D-configuration.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnh2decreases expressionEXP 6480464CTDGlucose results in decreased expression of KCNH2 proteinPMID:31729781
Kcnh2decreases activityISOKCNH2 (Homo sapiens)6480464CTDGlucose deficiency results in decreased activity of KCNH2 protein; Glucose results in decreased activity of KCNH2 proteinPMID:12531891
Kcnh2multiple interactionsISOKCNH2 (Homo sapiens)6480464CTD[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein; alpha-Tocopherol inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Deoxyglucose promotes the reaction [Glucose deficiency results in decreased activity of KCNH2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]; Pyruvic Acid inhibits the reaction [[Deoxyglucose co-treated with Glucose deficiency] results in decreased activity of KCNH2 protein]; Sodium Cyanide inhibits the reaction [Glucose results in decreased activity of KCNH2 protein]PMID:12531891
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