GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr1i3 | affects response to substance | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | NR1I3 gene affects the susceptibility to Toxaphene | PMID:26187448 | Nr1i3 | multiple interactions | ISO | Nr1i3 (Mus musculus) | 6480464 | CTD | NR1I3 gene mutant form inhibits the reaction [Toxaphene results in increased expression of CYP1A1 mRNA]; NR1I3 gene mutant form inhibits the reaction [Toxaphene results in increased expression of CYP1A2 mRNA]; NR1I3 gene mutant form inhibits the reaction [Toxaphene results in increased expression of CYP2B10 mRNA]; NR1I3 gene mutant form inhibits the reaction [Toxaphene results in increased expression of CYP2B9 mRNA]; NR1I3 gene mutant form inhibits the reaction [Toxaphene results in increased expression of CYP3A11 mRNA] | PMID:26187448 PMID:28218408 | |
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