GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Slco2b1 | increases import | ISO | SLCO2B1 (Homo sapiens) | 6480464 | CTD | SLCO2B1 protein results in increased import of estrone sulfate; SLCO2B1 results in increased import of estrone sulfate | PMID:16714376 PMID:20176623 PMID:27450509 | Slco2b1 | increases uptake | ISO | SLCO2B1 (Homo sapiens) | 6480464 | CTD | SLCO2B1 protein results in increased uptake of estrone sulfate | PMID:24285294 PMID:27504015 | Slco2b1 | multiple interactions | ISO | SLCO2B1 (Homo sapiens) | 6480464 | CTD | 2,2',4,4',5,6'-hexabromodiphenyl ether inhibits the reaction [SLCO2B1 results in increased import of estrone sulfate]; 2,2',4,4'-tetrabromodiphenyl ether inhibits the reaction [SLCO2B1 results in increased import of estrone sulfate]; [icariin results in decreased activity of SLCO2B1 protein] which results in decreased uptake of estrone sulfate; daidzein inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; daidzein metabolite inhibits the reaction [SLCO2B1 protein results in increased transport of estrone sulfate]; estrone sulfate inhibits the reaction [SLCO2B1 protein results in increased transport of daidzein metabolite]; estrone sulfate inhibits the reaction [SLCO2B1 protein results in increased uptake of Quercetin]; Mefloquine affects the reaction [SLCO2B1 protein results in increased uptake of estrone sulfate]; pentabromodiphenyl ether inhibits the reaction [SLCO2B1 results in increased import of estrone sulfate]; Rutin promotes the reaction [SLCO2B1 protein results in increased uptake of estrone sulfate]; Sulfobromophthalein inhibits the reaction [SLCO2B1 protein results in increased import of estrone sulfate]; Tobacco Smoke Pollution inhibits the reaction [SLCO2B1 protein results in increased import of estrone sulfate] | PMID:20176623 PMID:24265111 PMID:24285294 PMID:24947867 PMID:25319728 PMID:27450509 PMID:27504015 | | ||||||||||||||||||||||
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