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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621341
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nrg1
Name: neuregulin 1
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nrg1increases transportEXP 6480464CTDNRG1 protein results in increased transport of GlucosePMID:14711829
Nrg1multiple interactionsEXP 6480464CTD[NRG1 protein binds to ERBB3 protein] which results in increased transport of Glucose; MAPK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose]; MAPK3 protein promotes the reaction [NRG1 protein results in increased transport of Glucose]; PDK1 protein promotes the reaction [NRG1 protein results in increased transport of Glucose]; PRKCZ protein promotes the reaction [NRG1 protein results in increased transport of Glucose]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [NRG1 protein results in increased transport of Glucose]PMID:14711829
Nrg1multiple interactionsISONrg1 (Mus musculus)6480464CTD[lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose co-treated with 2,4-Dichlorophenoxyacetic Acid] results in increased expression of NRG1 mRNAPMID:37567420
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