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GENE - TERM ANNOTATION REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: DOID:9001472
Term: Nasal Polyps
Definition: Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.
Definition Source(s): MESH:D009298
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9 ISOMMP9 (Homo sapiens)8549735RGDassociated with Rhinosinusitis;mRNA:increased expression:nasal cavity mucosa  
Mmp9disease_progressionISOMMP9 (Homo sapiens)8657056RGD  
Mmp9susceptibilityISOMMP9 (Homo sapiens)5130861RGDassociated with Asthma, Aspirin-Induced; DNA:polymorphism:promoter: -1562C>T (human) 
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