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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621320
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:29365
Term: phosgene
Definition: An acyl chloride obtained by substitution of both hydrogens of formaldehyde by chlorine.
Chemical ID: MESH:D010705
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp9increases expressionEXP 6480464CTDPhosgene results in increased expression of MMP9 mRNA; Phosgene results in increased expression of MMP9 proteinPMID:21941784
Mmp9multiple interactionsEXP 6480464CTDDexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Phosgene results in increased expression of MMP9 protein]PMID:21941784
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