GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mmp9 | multiple interactions | EXP | | 6480464 | CTD | Ipratropium promotes the reaction [Formoterol Fumarate inhibits the reaction [Cadmium results in increased activity of MMP9 protein]] | PMID:20826145 | Mmp9 | affects expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Cadmium affects the expression of MMP9 mRNA | PMID:31154059 | Mmp9 | increases expression | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Cadmium results in increased expression of MMP9 mRNA; Cadmium results in increased expression of MMP9 protein | PMID:22884995 PMID:26514923 PMID:31646340 PMID:33559965 | Mmp9 | increases secretion | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | Cadmium results in increased secretion of MMP9 mRNA; Cadmium results in increased secretion of MMP9 protein | PMID:20049202 PMID:22626610 | Mmp9 | multiple interactions | ISO | MMP9 (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA]; 3-methyladenine inhibits the reaction [Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein]]; 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-3H-cyclopenta(c)quinoline inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP9 protein]; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased secretion of and results in decreased activity of MMP9 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP9 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 mRNA; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein; Cadmium results in increased expression of and results in increased activity of MMP9 protein; Curcumin inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA]; Deoxyglucose inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein]; ESR1 protein alternative form affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP9 protein]; GPER1 protein affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased activity of MMP9 protein]; Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein]; PKM protein affects the reaction [Lactic Acid promotes the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein]]; pyrazolanthrone inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA]; RTKI cpd inhibits the reaction [Cadmium results in increased expression of MMP9 mRNA] | PMID:26514923 PMID:31468104 PMID:33422613 PMID:34481905 PMID:36336208 | Mmp9 | multiple interactions | ISO | Mmp9 (Mus musculus) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MMP9 protein | PMID:31793751 | | ||||||||||||||||||||||
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