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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621314
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hspd1
Name: heat shock protein family D (Hsp60) member 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspd1affects expressionEXP 6480464CTDbisphenol A affects the expression of HSPD1 mRNAPMID:25181051
Hspd1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of HSPD1 mRNA; bisphenol A results in decreased expression of HSPD1 proteinPMID:30816183 PMID:32145629 PMID:32528016 PMID:34947998
Hspd1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Genistein] results in increased methylation of HSPD1 genePMID:28505145
Hspd1affects expressionISOHSPD1 (Homo sapiens)6480464CTDbisphenol A affects the expression of HSPD1 mRNAPMID:30903817
Hspd1decreases expressionISOHSPD1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of HSPD1 proteinPMID:34186270
Hspd1decreases expressionISOHspd1 (Mus musculus)6480464CTDbisphenol A results in decreased expression of HSPD1 mRNA; bisphenol A results in decreased expression of HSPD1 proteinPMID:24909818 PMID:26063408 PMID:33221593
Hspd1increases expressionISOHSPD1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of HSPD1 mRNAPMID:33670352
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