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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621303
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Atp2b1
Name: ATPase plasma membrane Ca2+ transporting 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Atp2b1affects splicingEXP 6480464CTDValproic Acid affects the splicing of ATP2B1 mRNAPMID:29427782
Atp2b1decreases expressionEXP 6480464CTDValproic Acid results in decreased expression of ATP2B1 mRNAPMID:33150595
Atp2b1increases methylationEXP 6480464CTDValproic Acid results in increased methylation of ATP2B1 promoterPMID:33150595
Atp2b1affects expressionISOATP2B1 (Homo sapiens)6480464CTDValproic Acid affects the expression of ATP2B1 mRNAPMID:25979313
Atp2b1increases expressionISOATP2B1 (Homo sapiens)6480464CTDValproic Acid results in increased expression of ATP2B1 mRNAPMID:23179753 PMID:25192806 PMID:28001369 PMID:29154799
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