GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Txn1 | decreases expression | EXP | | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in decreased expression of TXN protein; 1-Methyl-4-phenylpyridinium results in decreased expression of TXN1 protein | PMID:24140863 PMID:28082123 | Txn1 | decreases response to substance | EXP | | 6480464 | CTD | TXN protein results in decreased susceptibility to 1-Methyl-4-phenylpyridinium | PMID:24140863 | Txn1 | multiple interactions | EXP | | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in decreased expression of and results in increased oxidation of TXN1 protein; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Nicotine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN1 protein]]; methyllycaconitine inhibits the reaction [Nicotine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN1 protein]]; Nicotine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN1 protein]; TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein]; TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 protein]; TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein]; TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HSPA5 protein]; TXN protein affects the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TRAF2 protein] | PMID:20600802 PMID:24140863 PMID:28082123 | Txn1 | affects response to substance | ISO | Txn1 (Mus musculus) | 6480464 | CTD | TXN protein affects the susceptibility to 1-Methyl-4-phenylpyridinium | PMID:16099847 | Txn1 | decreases expression | ISO | TXN (Homo sapiens) | 6480464 | CTD | 1-Methyl-4-phenylpyridinium results in decreased expression of TXN mRNA; 1-Methyl-4-phenylpyridinium results in decreased expression of TXN protein | PMID:34732784 | Txn1 | decreases response to substance | ISO | TXN (Homo sapiens) | 6480464 | CTD | TXN protein results in decreased susceptibility to 1-Methyl-4-phenylpyridinium | PMID:24140863 | Txn1 | multiple interactions | ISO | TXN (Homo sapiens) | 6480464 | CTD | 1-methylpropyl-2-imidazolyl disulfide inhibits the reaction [schisanhenol inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN protein]]; geranylgeranylacetone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN mRNA]; geranylgeranylacetone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN protein]; schisanhenol inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN mRNA]; schisanhenol inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TXN protein]; TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of CASP12 protein]; TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ERN1 protein]; TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HSPA5 protein]; TXN protein inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TRAF2 protein] | PMID:24140863 PMID:34732784 | | ||||||||||||||||||||||
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