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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621032
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr0b2
Name: nuclear receptor subfamily 0, group B, member 2
Acc ID: CHEBI:4806
Term: (-)-epigallocatechin 3-gallate
Definition: A gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.
Chemical ID: MESH:C045651
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr0b2decreases expressionEXP 6480464CTDepigallocatechin gallate results in decreased expression of NR0B2 mRNAPMID:23146761
Nr0b2increases expressionISONR0B2 (Homo sapiens)6480464CTDepigallocatechin gallate results in increased expression of NR0B2 mRNAPMID:22178739
Nr0b2increases expressionISONr0b2 (Mus musculus)6480464CTDepigallocatechin gallate results in increased expression of NR0B2 mRNAPMID:22178739
Nr0b2multiple interactionsISONR0B2 (Homo sapiens)6480464CTDepigallocatechin gallate inhibits the reaction [Chenodeoxycholic Acid results in increased expression of NR0B2 mRNA]; epigallocatechin gallate inhibits the reaction [GW 4064 results in increased expression of NR0B2 mRNA]PMID:22178739
Nr0b2multiple interactionsISONr0b2 (Mus musculus)6480464CTDNR1H4 protein affects the reaction [epigallocatechin gallate results in increased expression of NR0B2 mRNA]PMID:22178739
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