GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nr0b2 | increases expression | ISO | Nr0b2 (Mus musculus) | 6480464 | CTD | pirinixic acid results in increased expression of NR0B2 mRNA | PMID:17426115 PMID:18445702 PMID:19176532 | Nr0b2 | multiple interactions | ISO | NR0B2 (Homo sapiens) | 6480464 | CTD | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NR0B2 mRNA | PMID:19710929 | Nr0b2 | multiple interactions | ISO | Nr0b2 (Mus musculus) | 6480464 | CTD | NR0B2 protein promotes the reaction [[Methionine deficiency co-treated with Choline deficiency co-treated with pirinixic acid] results in increased expression of CYP4A14 mRNA]; RXRA protein inhibits the reaction [pirinixic acid results in increased expression of NR0B2 mRNA] | PMID:19176532 PMID:19593819 | | ||||||||||||||||||||||
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