GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp8 | increases activity | EXP | | 6480464 | CTD | Gentamicins results in increased activity of CASP8 protein | PMID:17132701 | Casp8 | increases expression | EXP | | 6480464 | CTD | Gentamicins results in increased expression of CASP8 mRNA | PMID:33387578 | Casp8 | multiple interactions | EXP | | 6480464 | CTD | tetramethylpyrazine inhibits the reaction [Gentamicins results in increased activity of CASP8 protein]; tetramethylpyrazine inhibits the reaction [TNF protein promotes the reaction [Gentamicins results in increased expression of CASP8 protein]]; TNF protein promotes the reaction [Gentamicins results in increased expression of CASP8 protein] | PMID:17132701 | Casp8 | increases expression | ISO | CASP8 (Homo sapiens) | 6480464 | CTD | Gentamicins results in increased expression of CASP8 mRNA | PMID:29992668 | |
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